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Article

Chasing Mendel: five questions for personalized medicine.

The Journal of physiology - 1 Jun 2014

Joyner Michael J, Prendergast Franklyn G

Abstract excerpt

Ideas about personalized medicine are underpinned in part by evolutionary biology's Modern Synthesis. In this essay we link personalized medicine to the efforts of the early statistical investigators who quantified the heritability of human phenotype and then attempted to reconcile their observations with Mendelian genetics. As information about the heritability of common diseases was obtained, similar efforts...

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Identifiers

PMID: 24882820
DOI: 10.1113/jphysiol.2014.272336
PMCID: PMC4048096

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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