Article
HLA alleles associated with the adaptive immune response to smallpox vaccine: a replication study.
Human genetics - 1 Sept 2014
Ovsyannikova Inna G, Pankratz V Shane, Salk Hannah M, Kennedy Richard B, Poland Gregory A
Abstract excerpt
We previously reported HLA allelic associations with vaccinia virus (VACV)-induced adaptive immune responses in a cohort of healthy individuals (n = 1,071 subjects) after a single dose of the licensed smallpox (Dryvax) vaccine. This study demonstrated that specific HLA alleles were significantly associated with VACV-induced neutralizing antibody (NA) titers (HLA-B*13:02, *38:02, *44:03, *48:01, and...
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