Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

In utero depletion of fetal hematopoietic stem cells improves engraftment after neonatal transplantation in mice

31 May 2014

Abstract excerpt

Although in utero hematopoietic cell transplantation is a promising strategy to treat congenital hematopoietic disorders, levels of engraftment have not been therapeutic for diseases in which donor cells have no survival advantage. We used an antibody against the murine c-Kit receptor (ACK2) to deplete fetal host hematopoietic stem cells (HSCs) and increase space within the hematopoietic niche for donor cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hematopoietic Stem Cell Transplantation
Share to Mesenchymal stem cell research
Share to Pluripotent Stem Cells Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24879814
DOI: 10.1182/blood-2014-02-550327

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

In utero depletion of fetal hematopoietic stem cells improves engraftment after neonatal transplantation in micePMID 24879814Read ↗

In Utero Hematopoietic Stem Cell Transplant for Fanconi AnemiaSemantic proximity Read ↗

Antibody targeting KIT as pretransplantation conditioning in immunocompetent miceSemantic proximity Read ↗

Enhanced in utero allogeneic engraftment in mice after mobilizing fetal HSCs by α4β1/7 inhibitionSemantic proximity Read ↗

A novel Kit mutant rat enables hematopoietic stem cell engraftment without irradiation.Semantic proximity Read ↗

Kit regulates HSC engraftment across the human-mouse species barrier.Semantic proximity Read ↗

Fetal cells in the pregnant mouse are diverse and express a variety of progenitor and differentiated cell markers.Semantic proximity Read ↗

Uncoupling key determinants of hematopoietic stem cell engraftment through cell-specific and temporally controlled recipient conditioning.Semantic proximity Read ↗

Continuous cell supply from Krt7-expressing hematopoietic stem cells during native hematopoiesis revealed by targeted in vivo gene transfer method.Semantic proximity Read ↗

Disruption of placental ACKR3 impairs growth and hematopoietic development of offspring.Semantic proximity Read ↗

Brief Report: Complement C5a Promotes Human Embryonic Stem Cell Pluripotency in the Absence of FGF2Semantic proximity Read ↗

Long-Term Hematopoietic Engraftment of Congenic Amniotic Fluid Stem Cells After in Utero Intraperitoneal Transplantation to Immune Competent MiceSemantic proximity Read ↗

Optimized cell transplantation using adult rag2 mutant zebrafish.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.