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Interleukin-21 polymorphism affects gene expression and is associated with risk of ischemic stroke.

Inflammation - 1 Dec 2014

Li Guanggang, Xu Ruxiang, Cao Yinghua, Xie Xiaodong, Zheng Zhendong

Abstract excerpt

There has been more and more evidence to confirm the essential role of inflammatory processes in the development of ischemic stroke. Interleukin-21 (IL-21), the most recently discovered CD132-dependent cytokine, plays a key role in regulating inflammation. The aim of the study was to understand the association between IL-21 polymorphisms and ischemic stroke, and the effects of these polymorphisms on gene...

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PMID: 24879484
DOI: 10.1007/s10753-014-9935-9

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