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Article

Characterization of acetoin production in a budC gene disrupted mutant of Serratia marcescens G12.

Journal of industrial microbiology & biotechnology - 1 Aug 2014

Gao Songsong, Guo Wenyi, Shi Litao, Yu Yue, Zhang Cuikun, Yang Hongjiang

Abstract excerpt

The 2,3-butanediol (2,3-BD) dehydrogenase gene budC of Serratia marcescens G12 was disrupted to construct the acetoin (AC) producing strain G12M. In shake-flask cultures, AC production was enhanced by increased concentrations of glucose or sodium acetate in G12M. In fed-batch fermentation, G12M produced 47.5 g/L AC along with 9.8 g/L 2,3-BD. The expression of the key enzymes for AC synthesis was further...

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PMID: 24879481
DOI: 10.1007/s10295-014-1464-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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