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Article

Production of 2,3-dihydroxyisovalerate by Enterobacter cloacae.

Enzyme and microbial technology - 1 Oct 2020

Yang Yang, Zhang Zhongxi, Lu Xiyang, Gu Jinjie, Wang Yike, Yao Yao, Liao Xianyan, Shi Jiping, Lye Gary, Baganz Frank, Hao Jian

Abstract excerpt

2,3-Dihydroxyisovalerate is an intermediate of the valine synthesis pathway. However, neither natural microorganisms nor valine producing engineered strains have been reported yet to produce this chemical. Based on the 2,3-butanediol synthesis pathway, a biological route of 2,3-dihydroxyisovalerate production was developed using a budA and ilvD disrupted Klebsiella pneumoniae strain in our previous research. We...

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PMID: 32912674
DOI: 10.1016/j.enzmictec.2020.109650

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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