Article
Massively parallel pyrosequencing of the mitochondrial genome with the 454 methodology in forensic genetics.
Forensic science international. Genetics - 1 Sept 2014
Mikkelsen Martin, Frank-Hansen Rune, Hansen Anders J, Morling Niels
Abstract excerpt
RESULTS: of sequencing of whole mitochondrial genome, HV1 and HV2 DNA with the second generation system (SGS) Roche 454 GS Junior were compared with results of Sanger sequencing and SNP typing with SNaPshot single base extension detected with MALDI-TOF and capillary electrophoresis. We investigated the performance of the software analysis of the data, reproducibility, ability to sequence homopolymeric regions,...
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