Article
Quantification of mtDNA mixtures in forensic evidence material using pyrosequencing.
International journal of legal medicine - 1 Nov 2006
Andréasson H, Nilsson M, Budowle B, Frisk S, Allen M
Abstract excerpt
Analysis of mtDNA variation using Sanger sequencing does not allow accurate quantification of the components of mtDNA mixtures. An alternative method to determine the specific mixture ratios in samples displaying hetero-plasma, consisting of DNA contributions from several individuals, or containing contamination would therefore be valuable. A novel quantification system for mtDNA mixture analysis has been...
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