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Article

Pyrosequencing-based strategy for a successful SNP detection in two hypervariable regions: HV-I/HV-II of the human mitochondrial displacement loop.

Electrophoresis - 1 Jan 2010

Anjum Ghulam Murtza, Du Weidong, Klein Rachel, Amara Umme, Huber-Lang Markus, Schneider E Marion, Wiegand Peter

Abstract excerpt

Forensic analysis of mitochondrial displacement loop (D-loop) sequences using Sanger sequencing or SNP detection by minisequencing is well established. Pyrosequencing has become an important alternative because it enables high-throughput analysis and the quantification of individual mitochondrial DNAs (mtDNAs) in samples originating from more than one individual. DNA typing of the mitochondrial D-loop region is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 20084631
DOI: 10.1002/elps.200900325

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