Article
A multiplex allele-specific primer extension assay for forensically informative SNPs distributed throughout the mitochondrial genome.
International journal of legal medicine - 1 Jun 2004
Vallone Peter M, Just Rebecca S, Coble Michael D, Butler John M, Parsons Thomas J
Abstract excerpt
The typing of single nucleotide polymorphisms (SNPs) located throughout the mitochondrial genome (mtGenome) can help resolve individuals with an identical HV1/HV2 mitotype. A set of 11 SNPs selected for distinguishing individuals of the most common Caucasian HV1/HV2 mitotype were incorporated in an allele specific primer extension assay. The assay was optimized for multiplex detection of SNPs at positions 3010,...
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