Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Detection of promoter hypermethylation of Wnt antagonist genes in fecal samples for diagnosis of early colorectal cancer

1 Jan 2014

Abstract excerpt

AIM: To investigate the feasibility of detecting aberrantly hypermethylated Wnt-antagonist gene promoters (SFRP2 and WIF-1) in fecal DNA as non-invasive biomarkers for early colorectal cancer (CRC). METHODS: The methylation-specific polymerase chain reaction assay was performed to blindly analyze the methylation status of SFRP2 and WIF-1 gene promoters in fecal samples from 48 subjects with CRC, 35 with adenomas,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic factors in colorectal cancer
Share to Colorectal Cancer Screening and Detection
Share to Epigenetics and DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24876755
DOI: 10.3748/wjg.v20.i20.6329

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Detection of promoter hypermethylation of Wnt antagonist genes in fecal samples for diagnosis of early colorectal cancerPMID 24876755Read ↗

Methylation of SFRP2 gene as a promising noninvasive biomarker using feces in colorectal cancer diagnosis: a systematic meta-analysisSemantic proximity Read ↗

Hypermethylated SFRP2 gene in fecal DNA is a high potential biomarker for colorectal cancer noninvasive screeningSemantic proximity Read ↗

Detection of aberrant methylation in fecal DNA as a molecular screening tool for colorectal cancer and precancerous lesionsSemantic proximity Read ↗

Analysis of Fecal DNA Methylation to Detect Gastrointestinal NeoplasiaSemantic proximity Read ↗

Is methylation analysis of SFRP2 , TFPI2 , NDRG4 , and BMP3 promoters suitable for colorectal cancer screening in the Korean population?Semantic proximity Read ↗

Sensitive and Noninvasive Detection of Aberrant SFRP2 and MGMT-B Methylation in Iranian Patients with Colon Polyps.Semantic proximity Read ↗

DNA methylation analysis of SFRP2, GATA4/5, NDRG4 and VIM for the detection of colorectal cancer in fecal DNASemantic proximity Read ↗

Hypermethylation of SFRP2 as a Potential Marker for Stool-Based Detection of Colorectal Cancer and Precancerous LesionsSemantic proximity Read ↗

DNA methylation of SFRP1, SFRP2, and WIF1 and prognosis of postoperative colorectal cancer patientsSemantic proximity Read ↗

DNA Methylation Biomarkers for Noninvasive Diagnosis of Colorectal CancerSemantic proximity Read ↗

Analysis of DNA Methylation in Bowel Lavage Fluid for Detection of Colorectal CancerSemantic proximity Read ↗

Colorectal adenoma and cancer detection based on altered methylation pattern of SFRP1, SFRP2, SDC2 , and PRIMA1 in plasma samplesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.