Article
Evaluation of genetic association of the INK4 locus with primary open angle glaucoma in East Indian population.
Scientific reports - 30 May 2014
Vishal Mansi, Sharma Anchal, Kaurani Lalit, Chakraborty Subhadip, Ray Jharna, Sen Abhijit, Mukhopadhyay Arijit, Ray Kunal
Abstract excerpt
INK4 locus at chromosome 9p21 has been reported to be associated with primary open angle glaucoma (POAG) and its subtypes along with the associated optic disc parameters across the populations of European, Japanese and African ancestries. The locus encodes three tumor suppressor genes namely CDKN2A, ARF, CDKN2B and a long non-coding RNA CDKN2B-AS1 (also known as ANRIL). Here, we report association study of 34...
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