Article
Zinc finger protein 804A (ZNF804A) and verbal deficits in individuals with autism.
Journal of psychiatry & neuroscience : JPN - 1 Sept 2014
Anitha Ayyappan, Thanseem Ismail, Nakamura Kazuhiko, Vasu Mahesh M, Yamada Kazuo, Ueki Takatoshi, Iwayama Yoshimi, Toyota Tomoko, Tsuchiya Kenji J, Iwata Yasuhide, Suzuki Katsuaki, Sugiyama Toshiro, Tsujii Masatsugu, Yoshikawa Takeo, Mori Norio
Abstract excerpt
BACKGROUND: In a genome-wide association study of autism, zinc finger protein 804A (ZNF804A) single nucleotide polymorphisms (SNPs) were found to be nominally associated in verbally deficient individuals with autism. Zinc finger protein 804A copy number variations (CNVs) have also been observed in individuals with autism. In addition, ZNF804A is known to be involved in theory of mind (ToM) tasks, and ToM deficits...
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