Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional IRGM polymorphism is associated with language impairment in glioma and upregulates cytokine expressions.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Aug 2014

Ge Jing, Li Li, Jin Qi, Liu Yu Chen, Zhao Ludong, Song Hai-Han

Abstract excerpt

Immunity-related GTPase family M protein (IRGM) is a human protein recently highlighted for its contribution to autophagy upon infections. Evidences have shown that IRGM may also play critical roles in the pathogenesis of cancer. However, correlation between IRGM and glioma remains unclear. In the current study, we investigated two IRGM genetic polymorphisms, rs10065172C/T and rs13361189T/C, in glioma and their...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Interferon-gamma
Share to Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Brain Neoplasms

Share to Glioma

Share to GTP-Binding Proteins

Share to Interleukin-4

Share to Language Disorders

Share to Up-Regulation

Source

Identifiers

PMID: 24859836
DOI: 10.1007/s13277-014-2091-x

Genes

IRGM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional IRGM polymorphism is associated with language impairment in glioma and upregulates cytokine expressions.PMID 24859836Read ↗

Polymorphism in the IL4R gene and clinical features are associated with glioma prognosis: Analyses of case-cohort studies.Semantic proximity Read ↗

Immunity-related GTPase IRGM at the intersection of autophagy, inflammation, and tumorigenesis.Semantic proximity Read ↗

A novel functional polymorphism, 16974 A/C, in the interleukin-12-3' untranslated region is associated with risk of glioma.Semantic proximity Read ↗

Race-specific association of an IRGM risk allele with cytokine expression in human subjects.Semantic proximity Read ↗

Association between IL-13 Gene rs20541 Polymorphism and Glioma Susceptibility: A Meta-Analysis.Semantic proximity Read ↗

Association of autophagy-related IRGM polymorphisms with latent versus active tuberculosis infection in a Chinese population.Semantic proximity Read ↗

Evaluation of Immunity-related GTPase Family M Protein (IRGM) SNPs among Egyptian Lupus Patients: A Case-control Study.Semantic proximity Read ↗

IRGM gene polymorphisms and haplotypes associate with susceptibility of pulmonary tuberculosis in Chinese Hubei Han population.Semantic proximity Read ↗

Impact of IRGM gene promoter polymorphisms on susceptibility to chronic HBV infection.Semantic proximity Read ↗

Differential expression and clinical significance of three inflammation-related microRNAs in gangliogliomasSemantic proximity Read ↗

Autophagy gene polymorphism is associated with susceptibility to leprosy by affecting inflammatory cytokines.Semantic proximity Read ↗

Single Nucleotide Polymorphisms in IL-10, IL-12p40, and IL-13 Genes and Susceptibility to Glioma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.