Article
Impact of specific KRAS mutation in exon 2 on clinical outcome of chemotherapy- and radiotherapy-treated colorectal adenocarcinoma patients.
Molecular diagnosis & therapy - 1 Oct 2014
Roszkowski Krzysztof, Zurawski Bogdan, Jozwicki Wojciech, Basta Pawel, Lewandowska Marzena Anna
Abstract excerpt
BACKGROUND AND OBJECTIVES: Knowledge obtained via high-throughput technologies, used for tumor genome sequencing or identifying gene expression and methylation signatures, is clinically applicable thanks to molecular characterization in the context of tumor development and progression. This study was conducted to assess the impact of specific KRAS mutation in codons 12 and 13 on clinical outcome of chemotherapy...
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