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Article

Impact of FLT3(ITD) mutant allele level on relapse risk in intermediate-risk acute myeloid leukemia.

Blood - 10 Jul 2014

Linch David C, Hills Robert K, Burnett Alan K, Khwaja Asim, Gale Rosemary E

Abstract excerpt

Some studies have suggested that cases of acute myeloid leukemia (AML) with low levels of FLT3 internal tandem duplications (FLT3(ITD)) do not have a worse prognosis if there is a concomitant NPM1 mutation, although this is controversial. To clarify this therapeutically important issue, we have analyzed FLT3(ITD) and NPM1(MUT) levels in 1609 younger adult cases of cytogenetically intermediate-risk AML. The...

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Source

Identifiers

PMID: 24855211
DOI: 10.1182/blood-2014-02-554667

Genes

FLT3
NPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Impact of FLT3(ITD) mutant allele level on relapse risk in intermediate-risk acute myeloid leukemia.PMID 24855211Read ↗

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