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Article

Frequency of the ASP620ASN mutation in VPS35 and Arg1205His mutation in EIF4G1 in familial Parkinson's disease from South Italy.

Neurobiology of aging - 1 Oct 2014

Gagliardi Monica, Annesi Grazia, Tarantino Patrizia, Nicoletti Giuseppe, Quattrone Aldo

Abstract excerpt

Parkinson's disease (PD) is characterized by progressive loss of dopaminergic neurons in the substantia nigra pars compacta. This degeneration leads to bradykinesia, muscular rigidity, resting tremor, and postural instability. It affects 1%-2% of the population above the age of 60 years. Recently, 2 studies identified the Asp620Asn mutation in the vacuolar protein sorting 35 (VPS35) gene, and the Arg1205His in...

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Source

Identifiers

PMID: 24854799
DOI: 10.1016/j.neurobiolaging.2014.04.020

Genes

VPS35
SNCA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Frequency of the ASP620ASN mutation in VPS35 and Arg1205His mutation in EIF4G1 in familial Parkinson's disease from South Italy.PMID 24854799Read ↗

VPS35 Asp620Asn and EIF4G1 Arg1205His mutations are rare in Parkinson disease from southwest China.Semantic proximity Read ↗

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Whole exome sequencing of rare variants in EIF4G1 and VPS35 in Parkinson disease.Semantic proximity Read ↗

Vacuolar protein sorting 35 Asp620Asn mutation is rare in the ethnic Chinese population with Parkinson's disease.Semantic proximity Read ↗

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Frequency of the D620N mutation in VPS35 in Parkinson disease.Semantic proximity Read ↗

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