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Article

An essential ligand-binding domain in the membrane receptor for retinol-binding protein revealed by large-scale mutagenesis and a human polymorphism.

The Journal of biological chemistry - 30 May 2008

Kawaguchi Riki, Yu Jiamei, Wiita Patrick, Honda Jane, Sun Hui

Abstract excerpt

Plasma retinol-binding protein (RBP), the principal carrier of vitamin A in the blood, delivers vitamin A from liver, the site of storage, to distant organs that need vitamin A, such as the eye, brain, placenta, and testis. STRA6 is a high-affinity membrane receptor for RBP and mediates vitamin A uptake in these target organs. STRA6 is a 74-kDa multi-transmembrane domain protein that represents a new class of...

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Source

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Identifiers

PMID: 18387951
DOI: 10.1074/jbc.M801060200
PMCID: PMC2397481

Genes

STRA6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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An essential ligand-binding domain in the membrane receptor for retinol-binding protein revealed by large-scale mutagenesis and a human polymorphism.PMID 18387951Read ↗

The membrane receptor for plasma retinol-binding protein, a new type of cell-surface receptor.Semantic proximity Read ↗

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