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Article

Vitamin A metabolism in the retinal pigment epithelium: genes, mutations, and diseases.

Progress in retinal and eye research - 1 Sept 2003

Thompson Debra A, Gal Andreas

Abstract excerpt

Mutations in the genes necessary for the metabolism of vitamin A (all-trans retinol) and cycling of retinoids between the photoreceptors and retinal pigment epithelium (RPE) (the visual cycle) have recently emerged as an important class of genetic defects responsible for retinal dystrophies and dysfunctions. Research into the causes and treatment of diseases resulting from defects in retinal vitamin A metabolism...

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Source

Identifiers

PMID: 12892646
DOI: 10.1016/s1350-9462(03)00051-x

Genes

RPE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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