Article
Detection of HPV16 African variants and quantitative analysis of viral DNA methylation in oropharyngeal squamous cell carcinomas.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Jul 2014
Barbieri Daniela, Nebiaj Aurel, Strammiello Rosaria, Agosti Roberto, Sciascia Silvia, Gallinella Giorgio, Landini Maria Paola, Caliceti Umberto, Venturoli Simona
Abstract excerpt
BACKGROUND: HPV16 is the most prevalent genotype in oropharyngeal squamous cell carcinomas (OPSCCs), but there are few information about intratype variants prevalence and their clinical relevance in these tumors. Moreover, since HPV DNA detection alone is not sufficient to determine a favorable prognosis for OPSCCs, additional diagnostic/prognostic biomarkers are necessary. OBJECTIVES: To assess the prevalence of...
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