Article
The carbohydrate-binding domain of overexpressed STBD1 is important for its stability and protein-protein interactions.
Bioscience reports - 1 Jul 2014
Zhu Yuanqi, Zhang Mei, Kelly Amber Renee, Cheng Alan
Abstract excerpt
STBD1 (starch-binding domain-containing protein 1) belongs to the CBM20 (family 20 carbohydrate binding module) group of proteins, and is implicated in glycogen metabolism and autophagy. However, very little is known about its regulation or interacting partners. Here, we show that the CBM20 of STBD1 is crucial for its stability and ability to interact with glycogen-associated proteins. Mutation of a conserved...
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