Article
A conserved domain for glycogen binding in protein phosphatase-1 targeting subunits.
FEBS letters - 13 Nov 1998
Wu J, Liu J, Thompson I, Oliver C J, Shenolikar S, Brautigan D L
Abstract excerpt
The skeletal muscle glycogen-binding subunit (GM) of protein phosphatase-1 (PP1) is the founding member of a family of proteins that tether the PP1 catalytic subunit (PP1C) to glycogen and promote the dephosphorylation of glycogen synthase. A hydrophobic sequence (called here the VFV motif) is co...
Topics
- Amino Acid Sequence
- Animals
- Catalytic Domain
- Conserved Sequence
- Glutathione Transferase
- Glycogen
- Molecular Sequence Data
- Muscle, Skeletal
- Mutation
- Phosphoprotein Phosphatases
- Protein Conformation
- Protein Phosphatase 1