Article
A conserved domain for glycogen binding in protein phosphatase-1 targeting subunits.
FEBS letters - 13 Nov 1998
Wu J, Liu J, Thompson I, Oliver C J, Shenolikar S, Brautigan D L
Abstract excerpt
The skeletal muscle glycogen-binding subunit (GM) of protein phosphatase-1 (PP1) is the founding member of a family of proteins that tether the PP1 catalytic subunit (PP1C) to glycogen and promote the dephosphorylation of glycogen synthase. A hydrophobic sequence (called here the VFV motif) is conserved among GM, the liver subunit GL, and the widely expressed subunits, PTG, R5 and U5. This study analyzed the role...
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