Article
Overlapping phenotypes in complex spastic paraplegias SPG11, SPG15, SPG35 and SPG48.
Brain : a journal of neurology - 1 Jul 2014
Pensato Viviana, Castellotti Barbara, Gellera Cinzia, Pareyson Davide, Ciano Claudia, Nanetti Lorenzo, Salsano Ettore, Piscosquito Giuseppe, Sarto Elisa, Eoli Marica, Moroni Isabella, Soliveri Paola, Lamperti Elena, Chiapparini Luisa, Di Bella Daniela, Taroni Franco, Mariotti Caterina
Abstract excerpt
Hereditary spastic paraplegias are a heterogeneous group of neurodegenerative disorders, clinically classified in pure and complex forms. Genetically, more than 70 different forms of spastic paraplegias have been characterized. A subgroup of complicate recessive forms has been distinguished for the presence of thin corpus callosum and white matter lesions at brain imaging. This group includes several genetic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.