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Article

Frequency and phenotype of SPG11 and SPG15 in complicated hereditary spastic paraplegia.

Journal of neurology, neurosurgery, and psychiatry - 1 Dec 2009

Schüle R, Schlipf N, Synofzik M, Klebe S, Klimpe S, Hehr U, Winner B, Lindig T, Dotzer A, Riess O, Winkler J, Schöls L, Bauer P

Abstract excerpt

BACKGROUND: Hereditary spastic paraplegias (HSP) are clinically and genetically highly heterogeneous. Recently, two novel genes, SPG11 (spatacsin) and SPG15 (spastizin), associated with autosomal recessive HSP, were identified. Clinically, both are characterised by complicated HSP and a rather si...

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Source

Identifiers

PMID: 19917823
DOI: 10.1136/jnnp.2008.167528

Genes

SPG11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19917823-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Frequency and phenotype of SPG11 and SPG15 in complicated hereditary spastic paraplegia.PMID 19917823Read ↗

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