Article
An improved method for simple and efficient hepatitis B virus genome cloning.
Journal of virological methods - 1 Sept 2014
Tu Zeng, Hu Yuan, Xu Lei, Huang Yong, Luo Xuan, Hu Jie-Li, Huang Ai-Long
Abstract excerpt
The genetic variation of hepatitis B virus (HBV) is associated with a natural history of infection and with a response to antiviral therapy. Current attempts to investigate the genetic variation within patients infected with HBV have characterized only the subgenomic region or a limited number of full-length genomes. In this study, a simple and efficient full-length HBV cloning method, which is independent of...
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