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Article

Prostate anatomy in motheaten viable (me(v)) mice with mutations in the protein tyrosine phosphatase SHP-1.

Actas urologicas espanolas - 1 Sept 2014

García-Tello A, Angulo J C, Rodriguez-Ubreva J, Andrés G, López J I, Sánchez-Chapado M, López-Ruiz P, Colás B

Abstract excerpt

OBJECTIVE: To study prostate and seminal vesicle anatomy in viable motheaten (mev) with mutations in PTPN6 gene leading to a severe reduction in the activity of protein tyrosine phosphatase SHP-1. Homozygous mev mice exhibit multiple anomalies that include immunodeficiencies, increased proliferation of macrophage, neutrophil, and erythrocyte progenitors, decreased bone density and sterility. MATERIAL AND METHOD:...

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Identifiers

PMID: 24819344
DOI: 10.1016/j.acuro.2014.02.005

Genes

PTPN6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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