Article
Genetic Variation in NFKB1 and NFKBIA and Susceptibility to Coronary Artery Disease in a Chinese Uygur Population.
PloS one - 1 Jan 2015
Lai Hong-Mei, Li Xiao-Mei, Yang Yi-Ning, Ma Yi-Tong, Xu Rui, Pan Shuo, Zhai Hui, Liu Fen, Chen Bang-Dang, Zhao Qian
Abstract excerpt
OBJECTIVES: Coronary artery disease (CAD) is the most common chronic inflammatory disease worldwide. NF-κB, a central regulator of inflammation, is involved in various inflammatory diseases. The aim of this study was to investigate the association between NFKB1 and NFKBIA polymorphisms and the susceptibility to CAD and their impact on plasma levels of IL-6 in a Chinese Uygur population. METHODS: We genotyped...
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