Functional polymorphism of the NFKB1 gene promoter is related to the risk of dilated cardiomyopathy.

doi:10.1186/1471-2350-10-47

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Article

Functional polymorphism of the NFKB1 gene promoter is related to the risk of dilated cardiomyopathy.

BMC medical genetics - 31 May 2009

Zhou Bin, Rao Li, Peng Ying, Wang Yanyun, Li Yi, Gao Linbo, Chen Yu, Xue Hui, Song Yaping, Liao Miao, Zhang Lin

Abstract excerpt

BACKGROUND: Previous studies in experimental and human heart failure showed that nuclear factor kappa B (NF-kappaB) is chronically activated in cardiac myocytes, suggesting an important involvement of NF-kappaB in the cardiac remodeling process. A common insertion/deletion (-94 insertion/deletion ATTG, rs28362491) located between two putative key promoter regulatory elements in the NFKB1 gene was identified which...

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Identifiers

PMID: 19480714
DOI: 10.1186/1471-2350-10-47
PMCID: PMC2692851

Genes

NFKB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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