Article
Common EIF4E variants modulate risk for autism spectrum disorders in the high-functioning range.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Sept 2014
Waltes Regina, Gfesser Johannes, Haslinger Denise, Schneider-Momm Katja, Biscaldi Monica, Voran Anette, Freitag Christine M, Chiocchetti Andreas G
Abstract excerpt
The genetic architecture of Autism Spectrum Disorders (ASD) is complex. Common genetic variation has especially been related to high-functioning ASD. In addition, some studies favoured analysis of strictly diagnosed autism individuals, which resulted in more robust findings than the combined analysis of all spectrum individuals. Functional variants modulating EIF4E expression have previously been indicated as...
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