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Article

Shared genetic architecture and causality between autism spectrum disorder and irritable bowel syndrome, multisite pain, and fatigue.

Translational psychiatry - 23 Nov 2024

Li Yiran, Xie Tian, Vos Melissa, Snieder Harold, Hartman Catharina A

Abstract excerpt

Autism spectrum disorder (ASD) often co-occurs with functional somatic syndromes (FSS), such as irritable bowel syndrome (IBS), multisite pain, and fatigue. However, the underlying genetic mechanisms and causality have not been well studied. Using large-scale genome-wide association study (GWAS) data, we investigated the shared genetic architecture and causality between ASD and FSS. Specifically, we first...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39580447
DOI: 10.1038/s41398-024-03184-4
PMCID: PMC11585586

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