Article
Polymorphisms in FZD3 and FZD6 genes and risk of neural tube defects in a northern Han Chinese population.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology - 1 Nov 2014
Shi Ou-Yan, Yang Hui-Yun, Shen Yong-Ming, Sun Wei, Cai Chun-You, Cai Chun-Quan
Abstract excerpt
Neural tube defects (NTDs) are the most common and severe malformations of the central nervous system. The association of single nucleotide polymorphisms (SNPs) of the Frizzled 3 (FZD3) and Frizzled 6 (FZD6) genes and NTDs in the Han population of northern China was principally studied. One synonymous SNP (rs2241802) in FZD3 gene and three nonsynonymous SNPs (rs827528, rs3808553 and rs12549394) in FZD6 gene were...
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