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Article

Single nucleotide polymorphisms of PCP pathway related genes participate in the occurrence and development of neural tube defect.

Molecular genetics & genomic medicine - 1 Jan 2023

Liu Yan, Dong Liang, Zhi Xiufang, Liu Yang, Zhao Linsheng, Xu Xiaowei, Wang Lu, Zheng Jie, Pu Linjie, Gu Chunyu, Shu Jianbo, Cai Chunquan

Abstract excerpt

BACKGROUND: To screen the single nucleotide polymorphisms (SNPs) in the coding regions of VANGL and FZD family members related to the plane cell polarity (PCP) signaling pathway in neural tube defects (NTDs) patients, so as to provide theoretical and experimental basis for the prevention and treatment of NTDs by intervening PCP signal transduction. METHODS: 112 NTDs patients were collected as the case group and...

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Identifiers

PMID: 36378568
DOI: 10.1002/mgg3.2094
PMCID: PMC9834144

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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