Article
Structural insight into glucose dehydrogenase from the thermoacidophilic archaeon Thermoplasma volcanium.
Acta crystallographica. Section D, Biological crystallography - 1 May 2014
Kanoh Yoshitaka, Uehara Seiichiroh, Iwata Hideyuki, Yoneda Kazunari, Ohshima Toshihisa, Sakuraba Haruhiko
Abstract excerpt
Glucose dehydrogenase from the thermoacidophilic archaeon Thermoplasma volcanium (tvGlcDH) is highly active towards D-glucose and D-galactose, but does not utilize aldopentoses such as D-xylose as substrates. In the present study, the crystal structures of substrate/cofactor-free tvGlcDH and of a tvGlcDH T277F mutant in a binary complex with NADP and in a ternary complex with D-glucose and nicotinic acid adenine...
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