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Article

The p.V37I exclusive genotype of GJB2: a genetic risk-indicator of postnatal permanent childhood hearing impairment.

PloS one - 1 Jan 2012

Li Lei, Lu Jingrong, Tao Zheng, Huang Qi, Chai Yongchuan, Li Xiaohua, Huang Zhiwu, Li Yun, Xiang Mingliang, Yang Jun, Yao Guoyin, Wang Yu, Yang Tao, Wu Hao

Abstract excerpt

Postnatal permanent childhood hearing impairment (PCHI) is frequent (0.25%-0.99%) and difficult to detect in the early stage, which may impede the speech, language and cognitive development of affected children. Genetic tests of common variants associated with postnatal PCHI in newborns may provide an efficient way to identify those at risk. In this study, we detected a strong association of the p.V37I exclusive...

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Identifiers

PMID: 22574200
DOI: 10.1371/journal.pone.0036621
PMCID: PMC3344898

Genes

GJB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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