Article
Autoimmunity in atopic dermatitis: Biomarker or simply epiphenomenon?
8 May 2014
Abstract excerpt
The idea that a mechanism of autoimmunity could play a role in the pathogenesis of atopic dermatitis gained support from the observation that patients with atopic dermatitis display IgE reactivity to a variety of human protein antigens, several of which have been characterized at molecular level. A broad spectrum of at least 140 IgE-binding self-antigens associated with atopic dermatitis has been demonstrated;...
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