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Autoimmunity: the neoantigen hypothesis

27 Jun 2024

Abstract excerpt

Cracks in the 'loss of tolerance' conceptChapters and text books about autoimmunity typically begin with the statement that autoimmunity arises as a consequence of the 'loss of tolerance', which is described as intrinsic to T cells (1) and/or B cells (2), which, therefore, begin to react against selfantigens.On the surface this seems perfectly logical: the difference between a healthy young person with full...

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PMID: 38994353
DOI: 10.3389/fimmu.2024.1432985

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