Article
Humoral and Cellular Autoreactivity to Epidermal Proteins in Atopic Dermatitis.
Archivum immunologiae et therapiae experimentalis - 1 Dec 2016
Navarrete-Dechent Cristián, Pérez-Mateluna Guillermo, Silva-Valenzuela Sergio, Vera-Kellet Cristián, Borzutzky Arturo
Abstract excerpt
Atopic dermatitis (AD), a chronic relapsing inflammatory disease of the skin, is an important public health concern affecting 10-20 % of children worldwide. The etiology and pathogenesis of AD involve the interplay of genetic and environmental factors, including abnormalities in skin integrity and a skewed immune system usually driven by a Th2 phenotype in childhood with a switch to Th1 in the chronic phase of...
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