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Article

Expression of the primary angle closure glaucoma (PACG) susceptibility gene PLEKHA7 in endothelial and epithelial cell junctions in the eye.

Investigative ophthalmology & visual science - 6 May 2014

Lee Mei Chin, Chan Anita S Y, Goh Shuang Ru, Hilmy Maryam Hazly, Nongpiur Monisha E, Hong Wanjin, Aung Tin, Hunziker Walter, Vithana Eranga N

Abstract excerpt

PURPOSE: The role of the recently identified primary angle closure glaucoma (PACG) susceptibility gene, pleckstrin homology domain containing, family A member 7 (PLEKHA7), in PACG is unknown. PLEKHA7 associates with apical junctional complexes (AJCs) and is thus implicated in paracellular fluid regulation. We aimed to determine PLEKHA7's localization in the eye and its association with AJCs to elucidate its...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24801512
DOI: 10.1167/iovs.14-14145

Genes

PLEKHA7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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