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<i>CAHM</i>, a long non-coding RNA gene hypermethylated in colorectal neoplasia

5 May 2014

Abstract excerpt

The CAHM gene (Colorectal Adenocarcinoma HyperMethylated), previously LOC100526820, is located on chromosome 6, hg19 chr6:163 834 097-163 834 982. It lacks introns, encodes a long non-coding RNA (lncRNA) and is located adjacent to the gene QKI, which encodes an RNA binding protein. Deep bisulphite sequencing of ten colorectal cancer (CRC) and matched normal tissues demonstrated frequent hypermethylation within...

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PMID: 24799664
DOI: 10.4161/epi.29046

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