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Cytomegalovirus Replication in Semen Is Associated with Higher Levels of Proviral HIV DNA and CD4 <sup>+</sup> T Cell Activation during Antiretroviral Treatment

1 May 2014

Abstract excerpt

Asymptomatic cytomegalovirus (CMV) replication occurs frequently in the genital tract in untreated HIV-infected men and is associated with increased immune activation and HIV disease progression. To determine the connections between CMV-associated immune activation and the size of the viral reservoir, we evaluated the interactions between (i) asymptomatic seminal CMV replication, (ii) levels of T cell activation...

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PMID: 24789781
DOI: 10.1128/jvi.00831-14

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