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Article

Plasma Exosomes as Markers of Therapeutic Response in Patients with Acute Myeloid Leukemia

10 Apr 2014

Abstract excerpt

PURPOSE: Exosomes isolated from the plasma of newly diagnosed acute myeloid leukemia (AML) patients have elevated protein and transforming growth factor-beta 1 (TGF-β1) contents and inhibit natural killer (NK) cell cytotoxicity (Haematologica 96, p. 1302, 2011). A potential role of exosomes in predicting responses to chemotherapy (CT) was evaluated in AML patients undergoing treatment. EXPERIMENTAL DESIGN: Plasma...

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Identifiers

PMID: 24782865
DOI: 10.3389/fimmu.2014.00160

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