Article
IFNL3 (IL28B) and IFNL4 polymorphisms are associated with treatment response in Thai patients infected with HCV genotype 1, but not with genotypes 3 and 6.
Journal of medical virology - 1 Sept 2014
Akkarathamrongsin Srunthron, Thong Vo Duy, Payungporn Sunchai, Poovorawan Kittiyod, Prapunwattana Phisit, Poovorawan Yong, Tangkijvanich Pisit
Abstract excerpt
Recent studies have shown an association between single nucleotide polymorphisms (SNPs) in the interferon lambda-3 (IFNL3 or IL-28B) and IFNL4 genes and treatment response to hepatitis C virus genotype 1 (HCV-1) infection. The importance of these SNPs for HCV genotype 3 (HCV-3), and particularly HCV genotype 6 (HCV-6), remains to be elucidated. We analyzed a cohort of 225 Thai individuals with chronic HCV...
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