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Lack of testicular seipin causes teratozoospermia syndrome in men

28 Apr 2014

Abstract excerpt

Obesity impairs male fertility, providing evidence for a link between adipose tissue and reproductive function; however, potential consequences of adipose tissue paucity on fertility remain unknown. Lack of s.c. fat is a hallmark of Berardinelli-Seip congenital lipodystrophy type 2 (BSCL2), which is caused by mutations in BSCL2-encoding seipin. Mice with a targeted deletion of murine seipin model BSCL2 with...

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
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PMID: 24778225
DOI: 10.1073/pnas.1324025111

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Lack of testicular seipin causes teratozoospermia syndrome in menPMID 24778225Read ↗

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