Article
Mutation rate plasticity in rifampicin resistance depends on Escherichia coli cell-cell interactions.
Nature communications - 29 Apr 2014
Krašovec Rok, Belavkin Roman V, Aston John A D, Channon Alastair, Aston Elizabeth, Rash Bharat M, Kadirvel Manikandan, Forbes Sarah, Knight Christopher G
Abstract excerpt
Variation of mutation rate at a particular site in a particular genotype, in other words mutation rate plasticity (MRP), can be caused by stress or ageing. However, mutation rate control by other factors is less well characterized. Here we show that in wild-type Escherichia coli (K-12 and B strains), the mutation rate to rifampicin resistance is plastic and inversely related to population density: lowering...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.