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Article

Opposing effects of final population density and stress on Escherichia coli mutation rate.

The ISME journal - 1 Dec 2018

Krašovec Rok, Richards Huw, Gifford Danna R, Belavkin Roman V, Channon Alastair, Aston Elizabeth, McBain Andrew J, Knight Christopher G

Abstract excerpt

Evolution depends on mutations. For an individual genotype, the rate at which mutations arise is known to increase with various stressors (stress-induced mutagenesis-SIM) and decrease at high final population density (density-associated mutation-rate plasticity-DAMP). We hypothesised that these two forms of mutation-rate plasticity would have opposing effects across a nutrient gradient. Here we test this...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 30087411
DOI: 10.1038/s41396-018-0237-3
PMCID: PMC6230470

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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