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Article

Flow cytometry biomarkers distinguish DOCK8 deficiency from severe atopic dermatitis.

Clinical immunology (Orlando, Fla.) - 1 Feb 2014

Janssen Erin, Tsitsikov Erdyni, Al-Herz Waleed, Lefranc Gerard, Megarbane Andre, Dasouki Majed, Bonilla Francisco A, Chatila Talal, Schneider Lynda, Geha Raif S

Abstract excerpt

DOCK8 deficiency is a primary immunodeficiency characterized by recurrent sinopulmonary infections, dermatitis with cutaneous infections, elevated serum IgE levels, eosinophilia, and a high incidence of food allergy. Given the seriousness of DOCK8 deficiency, it is important to recognize it early and initiate appropriate therapy. Diagnosis relies on examining DOCK8 protein expression and sequencing of the 48...

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Source

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Identifiers

PMID: 24440647
DOI: 10.1016/j.clim.2013.12.006
PMCID: PMC3924424

Genes

DOCK8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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