Article
Breast cancer risk after radiotherapy for heritable and non-heritable retinoblastoma: a US-UK study.
British journal of cancer - 13 May 2014
Little M P, Schaeffer M L, Reulen R C, Abramson D H, Stovall M, Weathers R, de Vathaire F, Diallo I, Seddon J M, Hawkins M M, Tucker M A, Kleinerman R A
Abstract excerpt
BACKGROUND: Retinoblastoma is a rare childhood eye cancer caused by germline or somatic mutations in the RB1 gene. Previous studies observed elevated breast cancer risk among retinoblastoma survivors. However, there has been no research on breast cancer risk in relation to radiation (primarily scatter radiation from the primary treatment) and genetic susceptibility of retinoblastoma survivors. METHODS: Two groups...
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