Article
Risk of new cancers after radiotherapy in long-term survivors of retinoblastoma: an extended follow-up.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Apr 2005
Kleinerman Ruth A, Tucker Margaret A, Tarone Robert E, Abramson David H, Seddon Johanna M, Stovall Marilyn, Li Frederick P, Fraumeni Joseph F
Abstract excerpt
PURPOSE: Many children diagnosed with retinoblastoma (Rb) survive into adulthood and are prone to subsequent cancers, particularly hereditary patients, who have germline Rb-1 mutations. We have extended the follow-up of a large cohort of Rb patients for 7 more years to provide new information on the risk of additional cancers after radiotherapy in long-term survivors. PATIENTS AND METHODS: We analyzed the risk of...
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