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Article

Submersion and Hypoxia Inhibit Ciliated Cell Differentiation in a Notch-Dependent Manner

22 Apr 2014

Abstract excerpt

The epithelium that lines the conducting airways is composed of several distinct cell types that differentiate from common progenitor cells. The signals that control fate selection and differentiation of ciliated cells, a major component of the epithelium, are not completely understood. Ciliated cell differentiation can be accomplished in vitro when primary normal human bronchial epithelial (NHBE) cells are...

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PMID: 24754775
DOI: 10.1165/rcmb.2013-0237oc

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