Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Impact of aromatase genetic variation on hormone levels and global outcome after severe TBI.

Journal of neurotrauma - 15 Aug 2013

Garringer Julie A, Niyonkuru Christian, McCullough Emily H, Loucks Tammy, Dixon C Edward, Conley Yvette P, Berga Sarah, Wagner Amy K

Abstract excerpt

Although experimental traumatic brain injury (TBI) studies support estradiol as a neuroprotectant and potent stimulator of neuroplasticity, clinical studies suggest a negative association between endogenous estradiol profiles and mortality/poor outcomes. However, no studies have evaluated associations with cerebral spinal fluid (CSF) hormone profiles and aromatase gene (cytochrome P450 [CYP]19A1) variability on...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aromatase
Share to Biomarkers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Brain Injuries

Share to Estradiol

Share to Genetic Variation

Share to Severity of Illness Index

Share to Testosterone

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 23540392
DOI: 10.1089/neu.2012.2565
PMCID: PMC3741419

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impact of aromatase genetic variation on hormone levels and global outcome after severe TBI.PMID 23540392Read ↗

Genetic Variation and Impact on Outcome in Traumatic Brain Injury: an Overview of Recent Discoveries.Semantic proximity Read ↗

Sex and genetic associations with cerebrospinal fluid dopamine and metabolite production after severe traumatic brain injury.Semantic proximity Read ↗

Moderators of gene-outcome associations following traumatic brain injury.Semantic proximity Read ↗

Posttraumatic epilepsy: Integrating clinical, inflammatory, and genetic profiles in traumatic brain injury patients.Semantic proximity Read ↗

Genetic predictors of outcome following traumatic brain injury.Semantic proximity Read ↗

Impact of genetic polymorphisms on the risk of epilepsy amongst patients with acute brain injury: A systematic review.Semantic proximity Read ↗

A Dopamine Pathway Gene Risk Score for Cognitive Recovery Following Traumatic Brain Injury: Methodological Considerations, Preliminary Findings, and Interactions With Sex.Semantic proximity Read ↗

IL-1β associations with posttraumatic epilepsy development: a genetics and biomarker cohort study.Semantic proximity Read ↗

Post-Traumatic Brain Injury: Genetic Susceptibility to Outcome.Semantic proximity Read ↗

Coordinating Global Multi-Site Studies of Military-Relevant Traumatic Brain Injury: Opportunities, Challenges, and Harmonization GuidelinesSemantic proximity Read ↗

Protective effects of testosterone replacement therapy on brain tumor outcomes: the Mayo Clinic ExperienceSemantic proximity Read ↗

A genome-wide association study of outcome from traumatic brain injurySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.